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Bipolar Disorder: A Clinician's Guide to Treatment

First released in 2002. Routledge is an imprint of Taylor & Francis, an informa corporation.

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Bipolar Disorder: A Clinician's Guide to Treatment Management

First released in 2002. Routledge is an imprint of Taylor & Francis, an informa corporation.

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We have provided substantial data from coordinated in vitro studies indicating that liposome-mediated transfection of CNS cells can provide increases in mRNA and protein of neurotrophins (NGF, BDNF). We have shown that appropriate transfection protocols, which have minimal toxicity, can produce biologically active neurotrophins and enhance recovery from cholinergic deficiencies. Moreover, we have successfully transfected a reporter gene as well as neurotrophin genes into the uninjured and injured rat brain.

NIH] Hybridization: The genetic process of crossbreeding to produce a hybrid. Hybrid nucleic acids can be formed by nucleic acid hybridization of DNA and RNA molecules. Protein hybridization allows for hybrid proteins to be Studies 35 formed from polypeptide chains. [NIH] Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents. [NIH] Incubation: The development of an infectious disease from the entrance of the pathogen to the appearance of clinical symptoms.

EU] Gynecology: A medical-surgical specialty concerned with the physiology and disorders primarily of the female genital tract, as well as female endocrinology and reproductive physiology. [NIH] Hormones: Chemical substances having a specific regulatory effect on the activity of a certain organ or organs. The term was originally applied to substances secreted by various endocrine glands and transported in the bloodstream to the target organs. It is sometimes extended to include those substances that are not produced by the endocrine glands but that have similar effects.

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