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Biotechnology and Bioinformatics: Advances and Applications by Devarajan Thangadurai, Jeyabalan Sangeetha

By Devarajan Thangadurai, Jeyabalan Sangeetha

Reflecting the interdisciplinary nature of biotechnology, this e-book covers the function of particular supply of polymeric nanodrugs to melanoma cells, microbial detoxifying enzymes in bioremediation and bacterial plasmids in antimicrobial resistance. It addresses sleek developments reminiscent of pharmacogenomics, assessment of gene expression, recombinant proteins from methylotrophic yeast, identity of novel fermentation inhibitors of bioethanol creation, and polyhydroxyalkanoate established biomaterials. The publication highlights the sensible software of biotechnology and bioinformatics for bioenergy, creation of excessive price biochemicals, modeling molecular interactions, drug discovery, and custom-made medication.

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Extra resources for Biotechnology and Bioinformatics: Advances and Applications for Bioenergy, Bioremediation and Biopharmaceutical Research

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Cytotoxicity of paclitaxl incorporated in PLGA nanoparticles on hypoxic human tumor cells. Pharm Res 2009, 26, 1776–1784. Johnson, S. ; Laub, P. ; Beesley, J. ; Ozols, R. ; Hamilton, T. C. Increased platinumDNA damage tolerance is associated with cisplatin resistance and cross-resistance to various chemotherapeutic agents in unrelated human ovarian cancer cell lines. Cancer Res 1997, 57, 850–856. ; Perrut, M. Particle design using supercritical fluids: literature and patent survey. J Supercrit Fluids 2001, 20, 179–219.

Nguyen, C. ; Gurny, R. Synthesis of a novel fluorescent poly(d, l-lactide) end-capped with1-pyrenebutanol used for the preparation of nanoparticles. Eur J Pharm Sci 2003, 20, 217–222. ; Kawashima, Y. Preparations of biodegradable nanospheres of water-soluble and insoluble drugs with D, L-lactide/glycolide copolymer by a novel spontaneous emulsification solvent diffusion methodand the drug release behavior. J Control Rel 1993, 25, 89–98. ; Kwon, H. ; Lee, Y. ; Shin, S. ; Cho, C. ; Kim, C. K. Release of adriamycin from poly(benzyl-glutamate)/poly(ethylene oxide) nanoparticles.

Tsai, T. H. Curcumin and its nano-formulation: the kinetics of tissue distribution and blood-brain barrier penetration. Int. J. Pharm 2011, 416, 331–338. ; Alarcon, C. ; Alexander, C. Synthetic polymers as drugs and therapeutics. J Mater Chem 2005, 15, 441–455. Varkouhi, A. ; Mountrichas, R. ; Storm, G. Polyplexes based on cationic polymers with strong nucleic acid binding properties. Eur J Pharm Sci 2012, 45, 459–466. ; Okunieff, P. Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review.

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