By Teresa K. Attwood, Stephen R. Pettifer, David Thorne
This cutting edge ebook offers a totally clean exploration of bioinformatics, investigating its complicated interrelationship with biology and machine technological know-how. It methods bioinformatics from a special standpoint, highlighting interdisciplinary gaps that regularly seize the unwary.
The ebook considers how the necessity for organic databases drove the evolution of bioinformatics; it reports bioinformatics fundamentals (including database codecs, data-types and present research methods), and examines key themes in laptop technology (including data-structures, identifiers and algorithms), reflecting on their use and abuse in bioinformatics.
Bringing those disciplines jointly, this booklet is a vital learn when you desire to larger comprehend the demanding situations for bioinformatics on the interface of biology and desktop technological know-how, and the way to bridge the gaps. it will likely be a useful source for complex undergraduate and postgraduate scholars, and for academics, researchers and pros with an curiosity during this attention-grabbing, fast-moving self-discipline and the knotty difficulties that encompass it.
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Additional resources for Bioinformatics challenges at the interface of biology and computer science: mind the gap
1 Who first introduced the term bioinformatics? A Fred Sanger B Linus Pauling C Paulien Hogeweg D Margaret Dayhoff 2 Who first sequenced a protein? A Fred Sanger B Linus Pauling C Paulien Hogeweg D Margaret Dayhoff 3 How long did the determination of the sequence of insulin take? A Five months B Five years C Eight years D Ten years Chapter 1 Introduction 4 Which was the first enzyme whose amino acid sequence was determined? A Insulin B Ribonuclease C Myoglobin D Haemoglobin 5 Which was the first protein whose structure was determined?
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Acta Crystallographica, 6, 678–685; c) Molecular configuration in sodium thymonucleate. Nature, 171, 740–741. , Moore, S. H. (1960) the sequence of the amino acid residues in per formic acid‐oxidized ribonuclease. Journal of Biological Chemistry, 235, 633–647. Hogeweg, P. (1978) Simulating the growth of cellular forms. Simulation, 31, 90–96. Hogeweg, P. (2011) The roots of bioinformatics in theoretical biology. PLoS Computational Biology, 7(3), e1002021. Hogeweg, P. and Hesper, B. (1978) Interactive instruction on population interactions.