By Martin Röcken, Tilo Biedermann (auth.), Prof. Michael Hertl MD (eds.)
Autoimmune issues of the outside stay an enigma for plenty of clinicians and scientists now not acquainted with those quite often critical and protracted ailments. The ebook presents an outline and the most recent details at the vast spectrum of cutaneous autoimmune issues for clinicians, scientists and practitioners in dermatology, medication, rheumatology, ENT, pediatrics and ophthalmology. The publication is exclusive because it offers the state of the art wisdom on pathophysiology, scientific prognosis and administration of those problems supplied by way of the area specialists within the box. the first purpose is to develop the certainty of the pathophysiology of cutaneous autoimmune issues and to supply a realistic consultant to the right way to establish and deal with those stipulations. The ebook is illustrated with many tables, illustrative figures and scientific colour pictures. the second one variation has been prolonged by way of chapters on autoimmune pigmentary problems (vitiligo), hairloss (alopecia areata) and cutaneous signs of rheumatic disorders.
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Additional info for Autoimmune Diseases of the Skin: Pathogenesis, Diagnosis, Management
G. Hadjipavlou (✉) · P. G. Katonis · M. N. gr A. G. Hadjipavlou Division of Spine Surgery, Department of Orthopaedic Surgery, University of Texas Medical Branch at Galveston, Galveston, Texas, USA G. M. Tsoukas Department of Endocrinology, Montreal General Hospital, McGill University School of Medicine, Montreal, Quebec, Canada G. Sapkas School of Medicine, National University of Greece, Athens, Greece Principles of management of osteometabolic disorders affecting the aging spine Abstract Osteoporosis is the most common contributing factor of spinal fractures, which characteristically are not generally known to produce spinal cord compression symptoms.
Most new vertebral fractures, even painful ones, remain unrecognized by patients and their physicians. It is established that the presence of a vertebral fracture is a strong risk factor for subsequent osteoporotic fractures, and that those with low bone density and vertebral fractures are at highest risk. Large-scale clinical trials have demonstrated that osteoporosis therapies can reverse bone loss and reduce fracture rates, and that these benefits are most pronounced in patients with low BMD and vertebral fractures.
Bisphosphonates are the most popular antipagetic drug and several forms have been investigated. Keywords Osteoporosis · Fractures · Neurological deficit · Deformity · Paget’s disease · Back pain · Spinal stenosis · Myelopathy · Treatment 32 Introduction Osteoporosis and Paget’s disease of bone are two metabolic conditions that usually affect the aging population. The former is a very common skeletal disorder, whereas Paget’s disease affects about 3% of the population. This paper looks at both conditions.