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An Atlas of Osteoporosis, Third Edition by John C. Stevenson, Michael S. Marsh

By John C. Stevenson, Michael S. Marsh

The 3rd variation of this profitable Atlas of Osteoporosis is designed to supply a variety of physicians with a pictorial advisor to this significant disorder. The illustrations are a very good instructing source and the textual content offers a concise review to osteoporosis. For the 1st time, textual content and illustrations are totally built-in. The publication includes info of skeletal biology and the pathophysiology of osteoporosis, with a chain of diagrammatic and SEM illustrations. there's better emphasis on scientific elements during this version, quite in components resembling nutrients, workout, and progress. There also are very important sections on analysis utilizing bone densitometry and the laboratory review of bone issues.

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Sample text

However, the lean/bone mass ratios in mature men and women are similar, suggesting that both sexes at that time have an equal capacity to withstand mechanical trauma. Peak bone mass is largely determined by genetic factors. The variance in bone mineral density between dizygotic twins is much greater than in monozygotic twins5, and the daughters of women who have had a hip fracture have lower than average bone mineral density6. Genetic factors are almost certainly the reason for racial differences in bone mineral density, with a higher bone mineral density in blacks compared with whites7 and no evidence of a change in the incidence of osteoporosis in people who migrate from an area of low incidence to one of high incidence.

Gao Y, Qian WP, Dark K et al. Estrogen prevents bone loss through transforming growth factor beta signaling in T cells. Proc Natl Acad Sci USA 2004; 101: 16618–23. 7. Stevenson JC, Lindsay RL. Osteoporosis. London: Chapman & Hall, 1998. 21. Hughes DE, Dai A, Tiffee JC et al. Estrogen promotes apoptosis of murine osteoclasts mediated by TGF-beta. Nat Med 1996; 2: 1132–6. 8. Vaes G. Cellular biology and biochemical mechanisms of bone resorption. Clin Orthop 1988; 231: 239–71. 9. Russell RGG, Caswell AM, Hearn PR et al.

25. Kemmler W, Lauber D, Weineck J et al. Benefits of 2 years of intense exercise on bone density, physical fitness, and blood lipids in early postmenopausal osteopenic women: results of the Erlangen Fitness Osteoporosis Prevention Study (EFOPS). Arch Intern Med 2004; 164: 1084–91. 26. Pagani F, Francucci CM, Moro L. Markers of bone turnover: biochemical and clinical perspectives. J Endocrinol Invest 2005; 28 (10 Suppl): 8–13. 27. Seibel MJ, Cosman F, Shen V et al. Urinary hydroxypyridinium crosslinks of collagen as markers of bone resorption and estrogen efficacy in postmenopausal osteoporosis.

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